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Tbx4 function during hindlimb development reveals a mechanism that explains the origins of proximal limb defects
We dissect genetically a gene regulatory network that involves the transcription factors Tbx4, Pitx1 and Isl1 acting cooperatively to establish the hindlimb bud, and identify key differences in the pathways that initiate formation of the hindlimb and forelimb. Using live image analysis of murine lim...
Autores principales: | Duboc, Veronique, Sulaiman, Fatima A., Feneck, Eleanor, Kucharska, Anna, Bell, Donald, Holder-Espinasse, Muriel, Logan, Malcolm P. O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497778/ https://www.ncbi.nlm.nih.gov/pubmed/34423345 http://dx.doi.org/10.1242/dev.199580 |
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