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Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes

RNA binding proteins (RBPs) are essential for critical biological processes such as translation regulation and mRNA processing, and misfunctions of these proteins are associated with diseases such as cancer and neurodegeneration. SERBP1 (SERPINE1 mRNA Binding Protein 1) is an RBP that comprises two...

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Detalles Bibliográficos
Autores principales: Baudin, Antoine, Moreno-Romero, Alma K., Xu, Xiaoping, Selig, Emily E., Penalva, Luiz O. F., Libich, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497785/
https://www.ncbi.nlm.nih.gov/pubmed/34631798
http://dx.doi.org/10.3389/fmolb.2021.744707