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A Multifaceted Approach to Optimizing AAV Delivery to the Brain for the Treatment of Neurodegenerative Diseases

Despite major advancements in gene therapy technologies, there are no approved gene therapies for diseases which predominantly effect the brain. Adeno-associated virus (AAV) vectors have emerged as the most effective delivery vector for gene therapy owing to their simplicity, wide spread transductio...

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Detalles Bibliográficos
Autores principales: Fischell, Jonathan M., Fishman, Paul S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497810/
https://www.ncbi.nlm.nih.gov/pubmed/34630029
http://dx.doi.org/10.3389/fnins.2021.747726