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Fibroblast growth factor receptor 3 in hepatocytes protects from toxin-induced liver injury and fibrosis

The liver's remarkable regenerative capacity is orchestrated by several growth factors and cytokines. Fibroblast growth factor receptor 3 (Fgfr3) is frequently overexpressed in hepatocellular carcinoma and promotes cancer aggressiveness, whereas its role in liver homeostasis, repair and regener...

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Detalles Bibliográficos
Autores principales: Fearon, Abbie E., Slabber, Coenraad F., Kuklin, Andrii, Bachofner, Marc, Tortola, Luigi, Pohlmeier, Lea, Pantasis, Sophia, Hornemann, Thorsten, Chen, Lin, Kopf, Manfred, Werner, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497853/
https://www.ncbi.nlm.nih.gov/pubmed/34646985
http://dx.doi.org/10.1016/j.isci.2021.103143