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Sex Hormones and Aging Modulate Interferon Lambda 1 Production and Signaling by Human Uterine Epithelial Cells and Fibroblasts

Estradiol (E(2)) and progesterone (P) have potent effects on immune function in the human uterine endometrium which is essential for creating an environment conducive for successful reproduction. Type III/lambda (λ) interferons (IFN) are implicated in immune defense of the placenta against viral pat...

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Detalles Bibliográficos
Autores principales: Patel, Mickey V., Hopkins, Daniel C., Barr, Fiona D., Wira, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497887/
https://www.ncbi.nlm.nih.gov/pubmed/34630393
http://dx.doi.org/10.3389/fimmu.2021.718380