Rheological Impact of GBT1118 Cessation in a Sickle Mouse Model

In sickle cell disease (SCD), higher whole blood viscosity is a risk factor for vaso-occlusive crisis, avascular necrosis, and proliferative retinopathy. Blood viscosity is strongly impacted by hemoglobin (Hb) levels and red blood cell (RBC) deformability. Voxelotor is a hemoglobin S (HbS) polymeriz...

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Detalles Bibliográficos
Autores principales: Kanne, Celeste K., Nebor, Danitza, Pochron, Mira, Oksenberg, Donna, Sheehan, Vivien A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497897/
https://www.ncbi.nlm.nih.gov/pubmed/34630162
http://dx.doi.org/10.3389/fphys.2021.742784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497897/
https://www.ncbi.nlm.nih.gov/pubmed/34630162
http://dx.doi.org/10.3389/fphys.2021.742784

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