Targeting PI3K, FGFR, CDK4/6 Signaling Pathways Together With Cytostatics and Radiotherapy in Two Medulloblastoma Cell Lines

OBJECTIVES: Medulloblastoma (MB) is treated with surgery and chemotherapy, with or without irradiation, but unfortunately >20% of the patients are not cured, and treatment comes with serious long-term side effects, so novel treatments are urgently needed. Phosphoinositide 3-kinases (PI3K), fibrob...

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Detalles Bibliográficos
Autores principales: Lukoseviciute, Monika, Maier, Henrietta, Poulou-Sidiropoulou, Eleni, Rosendahl, Erika, Holzhauser, Stefan, Dalianis, Tina, Kostopoulou, Ourania N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497987/
https://www.ncbi.nlm.nih.gov/pubmed/34631586
http://dx.doi.org/10.3389/fonc.2021.748657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497987/
https://www.ncbi.nlm.nih.gov/pubmed/34631586
http://dx.doi.org/10.3389/fonc.2021.748657

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