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Targeting PI3K, FGFR, CDK4/6 Signaling Pathways Together With Cytostatics and Radiotherapy in Two Medulloblastoma Cell Lines
OBJECTIVES: Medulloblastoma (MB) is treated with surgery and chemotherapy, with or without irradiation, but unfortunately >20% of the patients are not cured, and treatment comes with serious long-term side effects, so novel treatments are urgently needed. Phosphoinositide 3-kinases (PI3K), fibrob...
Autores principales: | Lukoseviciute, Monika, Maier, Henrietta, Poulou-Sidiropoulou, Eleni, Rosendahl, Erika, Holzhauser, Stefan, Dalianis, Tina, Kostopoulou, Ourania N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497987/ https://www.ncbi.nlm.nih.gov/pubmed/34631586 http://dx.doi.org/10.3389/fonc.2021.748657 |
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