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Targeting mitochondria-inflammation circle by renal denervation reduces atheroprone endothelial phenotypes and atherosclerosis

OBJECTIVE: The disruption of mitochondrial redox homeostasis in endothelial cells (ECs) can cause chronic inflammation, a substantial contributor to the development of atherosclerosis. Chronic sympathetic hyperactivity can enhance oxidative stress to induce endothelial dysfunction. We determined if...

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Detalles Bibliográficos
Autores principales: Li, Zhuqing, Li, Qi, Wang, Li, Li, Chao, Xu, Mengping, Duan, Yajun, Ma, Likun, Li, Tingting, Chen, Qiao, Wang, Yilin, Wang, Yanxin, Feng, Jiaxin, Yin, Xuemei, Wang, Xiaolin, Han, Jihong, Lu, Chengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498003/
https://www.ncbi.nlm.nih.gov/pubmed/34607159
http://dx.doi.org/10.1016/j.redox.2021.102156