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Identification of a Gene Signature Closely Related to Immunosuppressive Tumour Microenvironment Predicting Prognosis of Patients in EGFR Mutant Lung Adenocarcinoma

Lung adenocarcinomas (LUADs) harbouring epidermal growth factor receptor (EGFR) mutations are generally unable to benefit from immune checkpoint inhibitors (ICIs) due to an immunosuppressive tumour microenvironment (TME) and a lower tumour mutation burden. Currently, no gene signature can comprehens...

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Detalles Bibliográficos
Autores principales: Li, Jia, Li, Huahua, Zhang, Chenyue, Zhang, Chenxing, Jiang, Lifeng, Wang, Haiyong, Liu, Huaimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498106/
https://www.ncbi.nlm.nih.gov/pubmed/34631565
http://dx.doi.org/10.3389/fonc.2021.732841