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Lynch Syndrome and MSI-H Cancers: From Mechanisms to “Off-The-Shelf” Cancer Vaccines

Defective DNA mismatch repair (dMMR) is associated with many cancer types including colon, gastric, endometrial, ovarian, hepatobiliary tract, urinary tract, brain and skin cancers. Lynch syndrome – a hereditary cause of dMMR – confers increased lifetime risk of malignancy in different organs and ti...

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Detalles Bibliográficos
Autores principales: Roudko, Vladimir, Cimen Bozkus, Cansu, Greenbaum, Benjamin, Lucas, Aimee, Samstein, Robert, Bhardwaj, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498209/
https://www.ncbi.nlm.nih.gov/pubmed/34630437
http://dx.doi.org/10.3389/fimmu.2021.757804