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Lynch Syndrome and MSI-H Cancers: From Mechanisms to “Off-The-Shelf” Cancer Vaccines
Defective DNA mismatch repair (dMMR) is associated with many cancer types including colon, gastric, endometrial, ovarian, hepatobiliary tract, urinary tract, brain and skin cancers. Lynch syndrome – a hereditary cause of dMMR – confers increased lifetime risk of malignancy in different organs and ti...
Autores principales: | Roudko, Vladimir, Cimen Bozkus, Cansu, Greenbaum, Benjamin, Lucas, Aimee, Samstein, Robert, Bhardwaj, Nina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498209/ https://www.ncbi.nlm.nih.gov/pubmed/34630437 http://dx.doi.org/10.3389/fimmu.2021.757804 |
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