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Interferon-gamma impairs phagocytosis of Escherichia coli by primary murine peritoneal macrophages stimulated with LPS and differentially modulates proinflammatory cytokine release

INTRODUCTION: Interferon-γ levels are increased upon viral infections and during inflamm-aging. Resistance to infections due to Escherichia coli (E. coli), a major cause of bacteriaemia and sepsis, is impaired in aged individuals, partly due to altered phagocytic capacity and cytokine release of imm...

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Detalles Bibliográficos
Autores principales: Schütze, Sandra, Kaufmann, Annika, Bunkowski, Stephanie, Ribes, Sandra, Nau, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498232/
https://www.ncbi.nlm.nih.gov/pubmed/34647015
http://dx.doi.org/10.1016/j.cytox.2021.100057