Activation of the cytosolic calcium-independent phospholipase A(2) β isoform contributes to TRPC6 externalization via release of arachidonic acid

During vascular interventions, oxidized low-density lipoprotein and lysophosphatidylcholine (lysoPC) accumulate at the site of arterial injury, inhibiting endothelial cell (EC) migration and arterial healing. LysoPC activates canonical transient receptor potential 6 (TRPC6) channels, leading to a pr...

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Detalles Bibliográficos
Autores principales: Putta, Priya, Smith, Andrew H., Chaudhuri, Pinaki, Guardia-Wolff, Rocio, Rosenbaum, Michael A., Graham, Linda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498464/
https://www.ncbi.nlm.nih.gov/pubmed/34509476
http://dx.doi.org/10.1016/j.jbc.2021.101180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498464/
https://www.ncbi.nlm.nih.gov/pubmed/34509476
http://dx.doi.org/10.1016/j.jbc.2021.101180

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