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Single‐Cell RNA‐Seq of T Cells in B‐ALL Patients Reveals an Exhausted Subset with Remarkable Heterogeneity

Characterization of functional T cell clusters is key to developing strategies for immunotherapy and predicting clinical responses in leukemia. Here, single‐cell RNA sequencing is performed with T cells sorted from the peripheral blood of healthy individuals and patients with B cell‐acute lymphoblas...

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Detalles Bibliográficos
Autores principales: Wang, Xiaofang, Chen, Yanjuan, Li, Zongcheng, Huang, Bingyan, Xu, Ling, Lai, Jing, Lu, Yuhong, Zha, Xianfeng, Liu, Bing, Lan, Yu, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498858/
https://www.ncbi.nlm.nih.gov/pubmed/34365737
http://dx.doi.org/10.1002/advs.202101447