Survival‐Assured Liver Injury Preconditioning (SALIC) Enables Robust Expansion of Human Hepatocytes in Fah (–/–) Rag2 (–/–) IL2rg (–/–) Rats

Although liver‐humanized animals are desirable tools for drug development and expansion of human hepatocytes in large quantities, their development is restricted to mice. In animals larger than mice, a precondition for efficient liver humanization remains preliminary because of different xeno‐repopu...

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Detalles Bibliográficos
Autores principales: Zhang, Ludi, Ge, Jian‐Yun, Zheng, Yun‐Wen, Sun, Zhen, Wang, Chenhua, Peng, Zhaoliang, Wu, Baihua, Fang, Mei, Furuya, Kinji, Ma, Xiaolong, Shao, Yanjiao, Ohkohchi, Nobuhiro, Oda, Tatsuya, Fan, Jianglin, Pan, Guoyu, Li, Dali, Hui, Lijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498896/
https://www.ncbi.nlm.nih.gov/pubmed/34382351
http://dx.doi.org/10.1002/advs.202101188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498896/
https://www.ncbi.nlm.nih.gov/pubmed/34382351
http://dx.doi.org/10.1002/advs.202101188

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