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The Transcription Factor SUB1 Is a Master Regulator of the Macrophage TLR Response in Atherosclerosis

Toll‐like receptor 2 and 4 (TLR2, TLR4) signaling is implicated in atherosclerotic plaque formation. The two‐stage master regulator Virtual Inference of Protein‐activity by Enriched Regulon (VIPER) analysis of macrophage TLR2 and TLR4 signature genes integrated with coexpression network genes derive...

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Detalles Bibliográficos
Autores principales: Huang, Rongzhong, Hu, Zicheng, Chen, Xiaorui, Cao, Yu, Li, Hongrong, Zhang, Hong, Li, Yongyong, Liang, Liwen, Feng, Yuxing, Wang, Ying, Su, Wenhua, Kong, Zerui, Melgiri, ND, Jiang, Lihong, Li, Xingsheng, Du, Jianlin, Chen, Yunqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8498911/
https://www.ncbi.nlm.nih.gov/pubmed/34378353
http://dx.doi.org/10.1002/advs.202004162