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Photocatalytic Hydroaminoalkylation of Styrenes with Unprotected Primary Alkylamines

[Image: see text] Catalytic, intermolecular hydroaminoalkylation (HAA) of styrenes provides a powerful disconnection for pharmacologically relevant γ-arylamines, but current methods cannot utilize unprotected primary alkylamines as feedstocks. Metal-catalyzed HAA protocols are also highly sensitive...

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Detalles Bibliográficos
Autores principales: Askey, Hannah E., Grayson, James D., Tibbetts, Joshua D., Turner-Dore, Jacob C., Holmes, Jake M., Kociok-Kohn, Gabriele, Wrigley, Gail L., Cresswell, Alexander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499025/
https://www.ncbi.nlm.nih.gov/pubmed/34543004
http://dx.doi.org/10.1021/jacs.1c07401