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EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression

BACKGROUND: During pregnancy, trophoblast cell invasion needs to be finely controlled. Aberrant trophoblast cell invasion is associated with placental diseases. Epidermal growth factor (EGF) and its receptor, EGFR, are expressed in trophoblast cells. Although the pro-invasive effect of EGF on tropho...

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Detalles Bibliográficos
Autores principales: Fang, Lanlan, Gao, Yibo, Wang, Zhen, Li, Yuxi, Yan, Yang, Wu, Ze, Cheng, Jung-Chien, Sun, Ying-Pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499481/
https://www.ncbi.nlm.nih.gov/pubmed/34620174
http://dx.doi.org/10.1186/s12964-021-00783-2