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EGF stimulates human trophoblast cell invasion by downregulating ID3-mediated KISS1 expression
BACKGROUND: During pregnancy, trophoblast cell invasion needs to be finely controlled. Aberrant trophoblast cell invasion is associated with placental diseases. Epidermal growth factor (EGF) and its receptor, EGFR, are expressed in trophoblast cells. Although the pro-invasive effect of EGF on tropho...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499481/ https://www.ncbi.nlm.nih.gov/pubmed/34620174 http://dx.doi.org/10.1186/s12964-021-00783-2 |