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Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8(+) T cell cytotoxicity in patients with gastric cancer

BACKGROUND: Toll-like receptors (TLRs) play central roles in the initiation of innate immune response, and also control adaptive immunity activation. Thus, the aim of the study was to investigate the regulation of TLR activation to CD8(+) T cells has not been fully elucidated in gastric cancer (GC)....

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Detalles Bibliográficos
Autores principales: Xu, Junli, Guo, Rongya, Jia, Jing, He, Yun, He, Shuixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499526/
https://www.ncbi.nlm.nih.gov/pubmed/34620075
http://dx.doi.org/10.1186/s12865-021-00459-z