Reciprocal deregulation of NKX3.1 and AURKA axis in castration-resistant prostate cancer and NEPC models

BACKGROUND: NKX3.1, a prostate-specific tumor suppressor, is either genomically lost or its protein levels are severely downregulated, which are invariably associated with poor prognosis in prostate cancer (PCa). Nevertheless, a clear disconnect exists between its mRNA and protein levels, indicating...

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Detalles Bibliográficos
Autores principales: Sooreshjani, Moloud Aflaki, Kamra, Mohini, Zoubeidi, Amina, Shah, Kavita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499580/
https://www.ncbi.nlm.nih.gov/pubmed/34625072
http://dx.doi.org/10.1186/s12929-021-00765-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8499580/
https://www.ncbi.nlm.nih.gov/pubmed/34625072
http://dx.doi.org/10.1186/s12929-021-00765-z

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