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Activation of mitochondrial unfolded protein response protects against multiple exogenous stressors

The mitochondrial unfolded protein response (mitoUPR) is an evolutionarily conserved pathway that responds to mitochondria insults through transcriptional changes, mediated by the transcription factor ATFS-1/ATF-5, which acts to restore mitochondrial homeostasis. In this work, we characterized the r...

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Detalles Bibliográficos
Autores principales: Soo, Sonja K, Traa, Annika, Rudich, Paige D, Mistry, Meeta, Van Raamsdonk, Jeremy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500221/
https://www.ncbi.nlm.nih.gov/pubmed/34583931
http://dx.doi.org/10.26508/lsa.202101182