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Loss of Resf1 reduces the efficiency of embryonic stem cell self-renewal and germline entry

Retroelement silencing factor 1 (RESF1) interacts with the key regulators of mouse embryonic stem cells (ESCs) OCT4 and NANOG, and its absence results in sterility of mice. However, the function of RESF1 in ESCs and germline specification is poorly understood. In this study, we used Resf1 knockout c...

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Detalles Bibliográficos
Autores principales: Vojtek, Matúš, Chambers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500223/
https://www.ncbi.nlm.nih.gov/pubmed/34607919
http://dx.doi.org/10.26508/lsa.202101190