SATB1-dependent mitochondrial ROS production controls TCR signaling in CD4 T cells

Special AT-rich sequence binding protein-1 (SATB1) is localized to the nucleus and remodels chromatin structure in T cells. SATB1-deficient CD4 T cells cannot respond to TCR stimulation; however, the cause of this unresponsiveness is to be clarified. Here, we demonstrate that SATB1 is indispensable...

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Detalles Bibliográficos
Autores principales: Kuwabara, Taku, Ishikawa, Fumio, Ikeda, Masataka, Ide, Tomomi, Kohwi-Shigematsu, Terumi, Tanaka, Yuriko, Kondo, Motonari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500228/
https://www.ncbi.nlm.nih.gov/pubmed/34583974
http://dx.doi.org/10.26508/lsa.202101093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500228/
https://www.ncbi.nlm.nih.gov/pubmed/34583974
http://dx.doi.org/10.26508/lsa.202101093

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