Cargando…
SATB1-dependent mitochondrial ROS production controls TCR signaling in CD4 T cells
Special AT-rich sequence binding protein-1 (SATB1) is localized to the nucleus and remodels chromatin structure in T cells. SATB1-deficient CD4 T cells cannot respond to TCR stimulation; however, the cause of this unresponsiveness is to be clarified. Here, we demonstrate that SATB1 is indispensable...
Autores principales: | Kuwabara, Taku, Ishikawa, Fumio, Ikeda, Masataka, Ide, Tomomi, Kohwi-Shigematsu, Terumi, Tanaka, Yuriko, Kondo, Motonari |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500228/ https://www.ncbi.nlm.nih.gov/pubmed/34583974 http://dx.doi.org/10.26508/lsa.202101093 |
Ejemplares similares
-
Increased Indoleamine 2,3-Dioxygenase Levels at the Onset of Sjögren’s Syndrome in SATB1-Conditional Knockout Mice
por: Tanaka, Yuriko, et al.
Publicado: (2021) -
An anti-silencer– and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development
por: Hao, Bingtao, et al.
Publicado: (2015) -
The Genomic Sequences Bound to Special AT-rich Sequence-binding Protein 1 (SATB1) In Vivo in Jurkat T Cells Are Tightly Associated with the Nuclear Matrix at the Bases of the Chromatin Loops
por: de Belle, Ian, et al.
Publicado: (1998) -
ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells
por: Ordinario, Ellen, et al.
Publicado: (2012) -
SATB1 establishes ameloblast cell polarity and regulates directional amelogenin secretion for enamel formation
por: Zhang, Yan, et al.
Publicado: (2019)