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Neddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles

Multivesicular bodies (MVBs) fuse with not only the plasma membranes to release extracellular vesicles (EVs) but also lysosomes for degradation. Rab7 participates in the lysosomal targeting of MVBs. However, the proteins on MVB that directly bind Rab7, causing MVB recruitment of Rab7 remain unidenti...

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Detalles Bibliográficos
Autores principales: Fei, Xuefeng, Li, Zhijie, Yang, Diya, Kong, Xianghui, Lu, Xinliang, Shen, Yingying, Li, Xu, Xie, Shaofang, Wang, Jiaoli, Zhao, Yongchao, Sun, Yi, Zhang, Jing, Ye, Zhaoming, Wang, Jianli, Cai, Zhijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500273/
https://www.ncbi.nlm.nih.gov/pubmed/34623756
http://dx.doi.org/10.1002/jev2.12153