By Increasing the Expression and Activation of STAT3, Sustained C5a Stimulation Increases the Proliferation, Migration, and Invasion of RCC Cells and Promotes the Growth of Transgrafted Tumors

BACKGROUND: Contradictive results about the direct role of C5a/C5aR1 axis in different cancer cells have been reported. The direct effect of C5a on human renal cell carcinoma (RCC) cells and the underlying mechanism are not clear. The aim of this study is to investigate the role of C5a/C5aR1 axis in...

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Detalles Bibliográficos
Autores principales: Zheng, Jing-Min, Zhou, Han-Xi, Yu, Hong-Yuan, Xia, Yu-Hui, Yu, Qing-Xin, Qu, Hang-Shuai, Bao, Jia-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500505/
https://www.ncbi.nlm.nih.gov/pubmed/34675657
http://dx.doi.org/10.2147/CMAR.S326352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500505/
https://www.ncbi.nlm.nih.gov/pubmed/34675657
http://dx.doi.org/10.2147/CMAR.S326352

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