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Transient lipid-bound states of spike protein heptad repeats provide insights into SARS-CoV-2 membrane fusion
Entry of SARS-CoV-2 into a host cell is mediated by spike, a class I viral fusion protein responsible for merging the viral and host cell membranes. Recent studies have revealed atomic-resolution models for both the postfusion 6-helix bundle (6HB) and the prefusion state of spike. However, a mechani...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Association for the Advancement of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500521/ https://www.ncbi.nlm.nih.gov/pubmed/34623907 http://dx.doi.org/10.1126/sciadv.abk2226 |