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Transient lipid-bound states of spike protein heptad repeats provide insights into SARS-CoV-2 membrane fusion

Entry of SARS-CoV-2 into a host cell is mediated by spike, a class I viral fusion protein responsible for merging the viral and host cell membranes. Recent studies have revealed atomic-resolution models for both the postfusion 6-helix bundle (6HB) and the prefusion state of spike. However, a mechani...

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Detalles Bibliográficos
Autores principales:	Chiliveri, Sai Chaitanya, Louis, John M., Ghirlando, Rodolfo, Bax, Ad
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2021
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500521/ https://www.ncbi.nlm.nih.gov/pubmed/34623907 http://dx.doi.org/10.1126/sciadv.abk2226

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