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The “original antigenic sin” and its relevance for SARS-CoV-2 (COVID-19) vaccination

Imprinting of the specific molecular image of a given protein antigen into immunological memory is one of the hallmarks of immunity. A later contact with a related, but different antigen should not trigger the memory response (because the produced antibodies would not be effective). The preferential...

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Detalles Bibliográficos
Autores principales: Rijkers, Ger T., van Overveld, Frans J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500682/
http://dx.doi.org/10.1016/j.clicom.2021.10.001