NaCT/SLC13A5 facilitates citrate import and metabolism under nutrient-limited conditions

Citrate lies at a critical node of metabolism, linking tricarboxylic acid metabolism and lipogenesis via acetyl-coenzyme A. Recent studies have observed that deficiency of the sodium-dependent citrate transporter (NaCT), encoded by SLC13A5, dysregulates hepatic metabolism and drives pediatric epilep...

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Detalles Bibliográficos
Autores principales: Kumar, Avi, Cordes, Thekla, Thalacker-Mercer, Anna E., Pajor, Ana M., Murphy, Anne N., Metallo, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500708/
https://www.ncbi.nlm.nih.gov/pubmed/34525352
http://dx.doi.org/10.1016/j.celrep.2021.109701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500708/
https://www.ncbi.nlm.nih.gov/pubmed/34525352
http://dx.doi.org/10.1016/j.celrep.2021.109701

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