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MACF1 controls skeletal muscle function through the microtubule-dependent localization of extra-synaptic myonuclei and mitochondria biogenesis

Skeletal muscles are composed of hundreds of multinucleated muscle fibers (myofibers) whose myonuclei are regularly positioned all along the myofiber’s periphery except the few ones clustered underneath the neuromuscular junction (NMJ) at the synaptic zone. This precise myonuclei organization is alt...

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Detalles Bibliográficos
Autores principales: Ghasemizadeh, Alireza, Christin, Emilie, Guiraud, Alexandre, Couturier, Nathalie, Abitbol, Marie, Risson, Valerie, Girard, Emmanuelle, Jagla, Christophe, Soler, Cedric, Laddada, Lilia, Sanchez, Colline, Jaque-Fernandez, Francisco-Ignacio, Jacquemond, Vincent, Thomas, Jean-Luc, Lanfranchi, Marine, Courchet, Julien, Gondin, Julien, Schaeffer, Laurent, Gache, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500715/
https://www.ncbi.nlm.nih.gov/pubmed/34448452
http://dx.doi.org/10.7554/eLife.70490