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Estimands in published protocols of randomised trials: urgent improvement needed

BACKGROUND: An estimand is a precise description of the treatment effect to be estimated from a trial (the question) and is distinct from the methods of statistical analysis (how the question is to be answered). The potential use of estimands to improve trial research and reporting has been underpin...

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Detalles Bibliográficos
Autores principales: Kahan, Brennan C., Morris, Tim P., White, Ian R., Carpenter, James, Cro, Suzie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500821/
https://www.ncbi.nlm.nih.gov/pubmed/34627347
http://dx.doi.org/10.1186/s13063-021-05644-4