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Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism

Thousands of outer-arm dyneins (OADs) are arrayed in the axoneme to drive a rhythmic ciliary beat. Coordination among multiple OADs is essential for generating mechanical forces to bend microtubule doublets (MTDs). Using electron microscopy, we determined high-resolution structures of Tetrahymena th...

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Detalles Bibliográficos
Autores principales: Rao, Qinhui, Han, Long, Wang, Yue, Chai, Pengxin, Kuo, Yin-wei, Yang, Renbin, Hu, Fangheng, Yang, Yuchen, Howard, Jonathon, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500839/
https://www.ncbi.nlm.nih.gov/pubmed/34556869
http://dx.doi.org/10.1038/s41594-021-00656-9