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Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism
Thousands of outer-arm dyneins (OADs) are arrayed in the axoneme to drive a rhythmic ciliary beat. Coordination among multiple OADs is essential for generating mechanical forces to bend microtubule doublets (MTDs). Using electron microscopy, we determined high-resolution structures of Tetrahymena th...
Autores principales: | Rao, Qinhui, Han, Long, Wang, Yue, Chai, Pengxin, Kuo, Yin-wei, Yang, Renbin, Hu, Fangheng, Yang, Yuchen, Howard, Jonathon, Zhang, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500839/ https://www.ncbi.nlm.nih.gov/pubmed/34556869 http://dx.doi.org/10.1038/s41594-021-00656-9 |
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