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P53 suppresses the progression of hepatocellular carcinoma via miR‐15a by decreasing OGT expression and EZH2 stabilization

Existing literature has highlighted the tumour suppressive capacity of microRNA‐15a (miR‐15a); however, its role in hepatocellular carcinoma (HCC) remains relatively unknown. This study aimed to investigate the role of miR‐15a in HCC and the associated underlying mechanism. Initially, RT‐qPCR was pe...

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Detalles Bibliográficos
Autores principales: You, Zhenyu, Peng, Dandan, Cao, Yixin, Zhu, Yuanzhe, Yin, Jianjun, Zhang, Guangxing, Peng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500955/
https://www.ncbi.nlm.nih.gov/pubmed/34510715
http://dx.doi.org/10.1111/jcmm.16792