MicroRNA‐205‐5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2‐mediated Beclin1 ubiquitination

Silicosis is an occupational disease characterized by extensive pulmonary fibrosis, and the underlying pathological process remains uncertain. Herein, we explored the molecular mechanism by which microRNA‐205‐5p (miR‐205‐5p) affects the autophagy of alveolar macrophages (AMs) and pulmonary fibrosis...

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Detalles Bibliográficos
Autores principales: Qian, Qingzeng, Ma, Qinghua, Wang, Bin, Qian, Qingqiang, Zhao, Changsong, Feng, Fumin, Dong, Xiaona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500965/
https://www.ncbi.nlm.nih.gov/pubmed/34428336
http://dx.doi.org/10.1111/jcmm.16825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500965/
https://www.ncbi.nlm.nih.gov/pubmed/34428336
http://dx.doi.org/10.1111/jcmm.16825

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