Cargando…
MicroRNA‐205‐5p targets E2F1 to promote autophagy and inhibit pulmonary fibrosis in silicosis through impairing SKP2‐mediated Beclin1 ubiquitination
Silicosis is an occupational disease characterized by extensive pulmonary fibrosis, and the underlying pathological process remains uncertain. Herein, we explored the molecular mechanism by which microRNA‐205‐5p (miR‐205‐5p) affects the autophagy of alveolar macrophages (AMs) and pulmonary fibrosis...
Autores principales: | Qian, Qingzeng, Ma, Qinghua, Wang, Bin, Qian, Qingqiang, Zhao, Changsong, Feng, Fumin, Dong, Xiaona |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500965/ https://www.ncbi.nlm.nih.gov/pubmed/34428336 http://dx.doi.org/10.1111/jcmm.16825 |
Ejemplares similares
-
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection
por: Gassen, Nils C., et al.
Publicado: (2019) -
USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1
por: Xu, Daichao, et al.
Publicado: (2016) -
The antioncogenic effect of Beclin-1 and FOXP3 is associated with SKP2 expression in gastric adenocarcinoma
por: Kim, Hyung Kyung, et al.
Publicado: (2021) -
SKP2 Contributes to AKT Activation by Ubiquitination Degradation of PHLPP1, Impedes Autophagy, and Facilitates the Survival of Thyroid Carcinoma
por: Shao, Yuan, et al.
Publicado: (2023) -
The antioncogenic effect of Beclin-1 and FOXP3 is associated with SKP2 expression in gastric adenocarcinoma: Erratum
Publicado: (2021)