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Generation of ‘designer erythroblasts’ lacking one or more blood group systems from CRISPR/Cas9 gene‐edited human‐induced pluripotent stem cells

Despite the recent advancements in transfusion medicine, red blood cell (RBC) alloimmunization remains a challenge for multiparous women and chronically transfused patients. At times, diagnostic laboratories depend on difficult‐to‐procure rare reagent RBCs for the identification of different alloant...

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Detalles Bibliográficos
Autores principales: Pandey, Priyanka, Zhang, Nanyan, Curtis, Brian R., Newman, Peter J., Denomme, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500969/
https://www.ncbi.nlm.nih.gov/pubmed/34547166
http://dx.doi.org/10.1111/jcmm.16872