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FAF1 downregulation by Toxoplasma gondii enables host IRF3 mobilization and promotes parasite growth

Fas‐associated factor 1 (FAF1) has gained a reputation as a member of the FAS death‐inducing signalling complex. However, the role of FAF1 in the immunity response is not fully understood. Here, we report that, in the human retinal pigment epithelial (RPE) cell line ARPE‐19 cells, FAF1 expression le...

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Detalles Bibliográficos
Autores principales: Gao, Fei‐Fei, Quan, Juan‐Hua, Choi, In‐Wook, Lee, Yeon‐Jae, Jang, Seul‐Gi, Yuk, Jae‐Min, Lee, Young‐Ha, Cha, Guang‐Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8500981/
https://www.ncbi.nlm.nih.gov/pubmed/34464509
http://dx.doi.org/10.1111/jcmm.16889