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Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice

Mammalian artificial chromosomes derived from native chromosomes have been applied to biomedical research and development by generating cell sources and transchromosomic (Tc) animals. Human artificial chromosome (HAC) is a precedent chromosomal vector which achieved generation of valuable humanized...

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Detalles Bibliográficos
Autores principales: Abe, Satoshi, Honma, Kazuhisa, Okada, Akane, Kazuki, Kanako, Tanaka, Hiroshi, Endo, Takeshi, Morimoto, Kayoko, Moriwaki, Takashi, Hamamichi, Shusei, Nakayama, Yuji, Suzuki, Teruhiko, Takehara, Shoko, Oshimura, Mitsuo, Kazuki, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501010/
https://www.ncbi.nlm.nih.gov/pubmed/34625612
http://dx.doi.org/10.1038/s41598-021-99535-y