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Construction of stable mouse artificial chromosome from native mouse chromosome 10 for generation of transchromosomic mice
Mammalian artificial chromosomes derived from native chromosomes have been applied to biomedical research and development by generating cell sources and transchromosomic (Tc) animals. Human artificial chromosome (HAC) is a precedent chromosomal vector which achieved generation of valuable humanized...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501010/ https://www.ncbi.nlm.nih.gov/pubmed/34625612 http://dx.doi.org/10.1038/s41598-021-99535-y |