BRAF mutations may identify a clinically distinct subset of glioblastoma

Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Prior studies examining the mutational landscape of GBM revealed recurrent alterations in genes that regulate the same growth control pathways. To this regard, ~ 40% of GBM harbor EGFR alterations, whereas BRAF variants a...

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Detalles Bibliográficos
Autores principales: McNulty, Samantha N., Schwetye, Katherine E., Ferguson, Cole, Storer, Chad E., Ansstas, George, Kim, Albert H., Gutmann, David H., Rubin, Joshua B., Head, Richard D., Dahiya, Sonika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501013/
https://www.ncbi.nlm.nih.gov/pubmed/34625582
http://dx.doi.org/10.1038/s41598-021-99278-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501013/
https://www.ncbi.nlm.nih.gov/pubmed/34625582
http://dx.doi.org/10.1038/s41598-021-99278-w

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