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p53-dependent induction of P2X7 on hematopoietic stem and progenitor cells regulates hematopoietic response to genotoxic stress

Stem and progenitor cells are the main mediators of tissue renewal and repair, both under homeostatic conditions and in response to physiological stress and injury. Hematopoietic system is responsible for the regeneration of blood and immune cells and is maintained by bone marrow-resident hematopoie...

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Detalles Bibliográficos
Autores principales: Tung, Lin Tze, Wang, HanChen, Belle, Jad I., Petrov, Jessica C., Langlais, David, Nijnik, Anastasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501024/
https://www.ncbi.nlm.nih.gov/pubmed/34625535
http://dx.doi.org/10.1038/s41419-021-04202-9