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p53-dependent induction of P2X7 on hematopoietic stem and progenitor cells regulates hematopoietic response to genotoxic stress
Stem and progenitor cells are the main mediators of tissue renewal and repair, both under homeostatic conditions and in response to physiological stress and injury. Hematopoietic system is responsible for the regeneration of blood and immune cells and is maintained by bone marrow-resident hematopoie...
Autores principales: | Tung, Lin Tze, Wang, HanChen, Belle, Jad I., Petrov, Jessica C., Langlais, David, Nijnik, Anastasia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501024/ https://www.ncbi.nlm.nih.gov/pubmed/34625535 http://dx.doi.org/10.1038/s41419-021-04202-9 |
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