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Comprehensive RNA analysis of CSF reveals a role for CEACAM6 in lung cancer leptomeningeal metastases

Non-small cell lung cancer (NSCLC) metastatic to the brain leptomeninges is rapidly fatal, cannot be biopsied, and cancer cells in the cerebrospinal fluid (CSF) are few; therefore, available tissue samples to develop effective treatments are severely limited. This study aimed to converge single-cell...

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Detalles Bibliográficos
Autores principales: Li, Yingmei, Polyak, Dina, Lamsam, Layton, Connolly, Ian David, Johnson, Eli, Khoeur, Lina Khav, Andersen, Stephanie, Granucci, Monica, Stanley, Geoff, Liu, Boxiang, Nagpal, Seema, Hayden Gephart, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501028/
https://www.ncbi.nlm.nih.gov/pubmed/34625644
http://dx.doi.org/10.1038/s41698-021-00228-6