Hypermethylation of Mest promoter causes aberrant Wnt signaling in patients with Alzheimer’s disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia and behavioral changes. Extracellular deposition of amyloid plaques (Aβ) and intracellular deposition of neurofibrillary tangles in neurons are the major pathogenicities of AD. However, drugs targeting t...

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Detalles Bibliográficos
Autores principales: Prasad, Renuka, Jung, Hwajin, Tan, Anderson, Song, Yonghee, Moon, Sungho, Shaker, Mohammed R., Sun, Woong, Lee, Junghee, Ryu, Hoon, Lim, Hyun Kook, Jho, Eek-hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501037/
https://www.ncbi.nlm.nih.gov/pubmed/34625606
http://dx.doi.org/10.1038/s41598-021-99562-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501037/
https://www.ncbi.nlm.nih.gov/pubmed/34625606
http://dx.doi.org/10.1038/s41598-021-99562-9

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