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Stage-resolved Hi-C analyses reveal meiotic chromosome organizational features influencing homolog alignment

During meiosis, chromosomes exhibit dramatic changes in morphology and intranuclear positioning. How these changes influence homolog pairing, alignment, and recombination remain elusive. Using Hi-C, we systematically mapped 3D genome architecture throughout all meiotic prophase substages during mous...

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Detalles Bibliográficos
Autores principales: Zuo, Wu, Chen, Guangming, Gao, Zhimei, Li, Shuai, Chen, Yanyan, Huang, Chenhui, Chen, Juan, Chen, Zhengjun, Lei, Ming, Bian, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501046/
https://www.ncbi.nlm.nih.gov/pubmed/34625553
http://dx.doi.org/10.1038/s41467-021-26033-0