Cargando…

An oncolytic virus expressing a full-length antibody enhances antitumor innate immune response to glioblastoma

Oncolytic herpes simplex virus-1 is capable of lysing tumor cells while alerting the immune system. CD47, in collaboration with SIRPα, represents an important immune checkpoint to inhibit phagocytosis by innate immune cells. Here we show locoregional control of glioblastoma by an oncolytic herpes vi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Bo, Tian, Lei, Chen, Jing, Wang, Jing, Ma, Rui, Dong, Wenjuan, Li, Aimin, Zhang, Jianying, Antonio Chiocca, E., Kaur, Balveen, Feng, Mingye, Caligiuri, Michael A., Yu, Jianhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501058/ https://www.ncbi.nlm.nih.gov/pubmed/34625564 http://dx.doi.org/10.1038/s41467-021-26003-6

Ejemplares similares

Deciphering the Multifaceted Relationship between Oncolytic Viruses and Natural Killer Cells
por: Alvarez-Breckenridge, Christopher A., et al.
Publicado: (2012)

An oncolytic herpes virus expressing E-cadherin resists NK cell clearance and improves viral spread and glioblastoma virotherapy
por: Xu, Bo, et al.
Publicado: (2018)

STAT3 Activation Promotes Oncolytic HSV1 Replication in Glioma Cells
por: Okemoto, Kazuo, et al.
Publicado: (2013)

PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance
por: Russell, Luke, et al.
Publicado: (2018)

PKR induces TGF-β and limits oncolytic immune therapy
por: Hong, Bangxing, et al.
Publicado: (2023)

CAR-Engineered NK Cells Targeting Wild-Type EGFR and EGFRvIII Enhance Killing of Glioblastoma and Patient-Derived Glioblastoma Stem Cells
por: Han, Jianfeng, et al.
Publicado: (2015)

ATN-224 enhances antitumor efficacy of oncolytic herpes virus against both local and metastatic head and neck squamous cell carcinoma
por: Yoo, Ji Young, et al.
Publicado: (2015)

A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases
por: Chen, Xilin, et al.
Publicado: (2016)

Uncovering a novel mechanism whereby NK cells interfere with glioblastoma virotherapy
por: Alvarez-Breckenridge, Christopher A., et al.
Publicado: (2013)

Oncolytic Virus Therapy Alters the Secretome of Targeted Glioblastoma Cells
por: Godlewski, Jakub, et al.
Publicado: (2021)

Replication and Spread of Oncolytic Herpes Simplex Virus in Solid Tumors
por: Hong, Bangxing, et al.
Publicado: (2022)

Dependence of innate lymphoid cell 1 development on NKp46
por: Wang, Yufeng, et al.
Publicado: (2018)

The current status of oncolytic viral therapy for head and neck cancer
por: Old, Matthew O., et al.
Publicado: (2016)

Oncolytic Newcastle disease virus activation of the innate immune response and priming of antitumor adaptive responses in vitro
por: Burke, Shannon, et al.
Publicado: (2020)

Updates to the antitumor mechanism of oncolytic virus
por: Bai, Yang, et al.
Publicado: (2019)

Oncolytic viruses on the cusp of success?: proceedings of the 9th International Conference on Oncolytic Virus Therapeutics
por: Peters, Cole, et al.
Publicado: (2016)

Tumor-Associated Macrophages/Microglia in Glioblastoma Oncolytic Virotherapy: A Double-Edged Sword
por: Blitz, Sarah E., et al.
Publicado: (2022)

Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy
por: Jenner, Adrianne L., et al.
Publicado: (2022)

oHSV-P10 reduces glioma stem cell enrichment after oncolytic HSV therapy
por: Sahu, Upasana, et al.
Publicado: (2023)

Aptamers Enhance Oncolytic Viruses’ Antitumor Efficacy
por: Dymova, Maya A., et al.
Publicado: (2022)

Combining HDAC inhibitors with oncolytic virotherapy for cancer therapy
por: Nakashima, Hiroshi, et al.
Publicado: (2015)

The complex relationship between integrins and oncolytic herpes Simplex Virus 1 in high-grade glioma therapeutics
por: Rivera-Caraballo, Kimberly Ann, et al.
Publicado: (2022)

Choindroitinase ABC I-Mediated Enhancement of Oncolytic Virus Spread and Anti Tumor Efficacy: A Mathematical Model
por: Kim, Yangjin, et al.
Publicado: (2014)

Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma
por: Saha, Dipongkor, et al.
Publicado: (2020)

Oncolytic Virus-Induced Autophagy in Glioblastoma
por: Kamynina, Margarita, et al.
Publicado: (2021)

Clinical trial links oncolytic immunoactivation to survival in glioblastoma
por: Ling, Alexander L., et al.
Publicado: (2023)

Modeling Oncolytic Viral Therapy, Immune Checkpoint Inhibition, and the Complex Dynamics of Innate and Adaptive Immunity in Glioblastoma Treatment
por: Storey, Kathleen M., et al.
Publicado: (2020)

The Role of the Innate Immune System in Oncolytic Virotherapy
por: Phan, Tuan Anh, et al.
Publicado: (2017)

Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity
por: Lin, Jing, et al.
Publicado: (2023)

Antibodies to Full-Length Agrin Protein in Chinese Patients With Myasthenia Gravis
por: Wang, Shumin, et al.
Publicado: (2021)

Current strategies in engaging oncolytic viruses with antitumor immunity
por: Boagni, Drew Ashton, et al.
Publicado: (2021)

An oncolytic adenovirus that expresses the HAb18 and interleukin 24 genes exhibits enhanced antitumor activity in hepatocellular carcinoma cells
por: Yuan, Sujing, et al.
Publicado: (2016)

Glioblastoma microenvironment and its reprogramming by oncolytic virotherapy
por: Qi, Zhongbing, et al.
Publicado: (2022)

PTEN potentiation of oncolytic HSV therapy for glioblastoma
por: Migliarese, Christian, et al.
Publicado: (2023)

IM-4 Impact of oHSV activated NOTCH signaling in tumor microenvironment and its impact on anti-tumor immunity
por: Yoshihiro, Otani, et al.
Publicado: (2021)

Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models
por: Koch, Marilin S, et al.
Publicado: (2022)

Improving antitumor efficacy via combinatorial regimens of oncolytic virotherapy
por: Zhang, Bin, et al.
Publicado: (2020)

Reporter Transgenes for Monitoring the Antitumor Efficacy of Recombinant Oncolytic Viruses
por: Semenova, A. V., et al.
Publicado: (2022)

The RNA m(6)A reader YTHDF2 controls NK cell antitumor and antiviral immunity
por: Ma, Shoubao, et al.
Publicado: (2021)

Enhanced Antitumor Efficacy of an Oncolytic Herpes Simplex Virus Expressing an Endostatin–Angiostatin Fusion Gene in Human Glioblastoma Stem Cell Xenografts
por: Zhang, Guobin, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_9tjokkqmh6tolsgn6hfa1vi4kt