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Mechanism of RNA polymerase III termination-associated reinitiation-recycling conferred by the essential function of the N terminal-and-linker domain of the C11 subunit

RNA polymerase III achieves high level tRNA synthesis by termination-associated reinitiation-recycling that involves the essential C11 subunit and heterodimeric C37/53. The C11-CTD (C-terminal domain) promotes Pol III active center-intrinsic RNA 3′-cleavage although deciphering function for this act...

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Detalles Bibliográficos
Autores principales: Mishra, Saurabh, Hasan, Shaina H., Sakhawala, Rima M., Chaudhry, Shereen, Maraia, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8501072/
https://www.ncbi.nlm.nih.gov/pubmed/34625550
http://dx.doi.org/10.1038/s41467-021-26080-7